We are looking for an Upstream Process Development Science Manager to join us at our site in Nottingham.

We are looking for an Upstream Process Development Science Manager to join the Technical Support Group at Albumedix, now part of Sartorius. In this role, you will be responsible for leading a small close-knit team in upstream processing activities to produce recombinant protein products in small and pilot scale fermentation.

The overall team in the Technical Support Group consists of 15 professionals, and we are looking forward to shaping the future with you. The site is expanding so it’s a great time to join the team to further your career.

This position is available full-time. It is an onsite role in central Nottingham and the site is easy to get to, being a short walk from the trains station and tram stop.

Grow with us – Your Responsibilities

• You will be responsible for management of the upstream process development team, training and mentoring staff in the group and when required in the wider organisation

• You will also implement individual development plans, goal setting and performance review for the team

• You will spend most of your time in the research laboratory to provide technical support for biopharmaceutical manufacturing of recombinant human albumin products, expert analysis of upstream process steps (shake -flask, seeds, main fermenter, cell separation) as well as new product development

• You will lead upstream activities, perform troubleshooting, and process optimization using scale down fermentation studies, with subsequent implementation at production scale.

• You will implement process improvements with respect to yield, efficiency and/or robustness

• Identifying process optimisation activities, including Design of Experiments (DoE), performing scale down studies, and management of their implementation at large scale

• Carrying out fermentation experiments using different scale benchtop bioreactors (2L) and pilot bioreactors (20-200L), this includes SIP, CIP, media preparation, seeding, inoculation, fermentation monitoring, microbial, chemical analysis and harvesting

• Review of batch process data and contribute to continued process verification

• Support technology transfer projects for cGMP manufacturing to other sites

• Investigation and recommending of new technologies to use in upstream processes

• In addition, you will provide fermentation support to cGMP cell bank testing, as well as generating albumin-based products for enhanced service projects and for application areas

• You will prepare, test and release laboratory growth media, preparing reagents and buffers as necessary as well as interpret results, prepare data summaries and reports and recommend future actions

What will convince us

• PhD degree in Fermentation, Biotechnology, Microbiology, Biosciences, Life Sciences or related discipline with at least 5 years of relevant fermentation industry experience or MSc degree with at least 10 years relevant fermentation industry experience

• Experience leading or supervising a small team would be essential

• Experience in microbial fermentation, preferably yeast fermentation would be essential

• Experience in aerobic fermentation would be desirable

• Good understanding of fermentation, growth rates, process optimization, developing and scaling processes

• Well-developed independent research skills, including statistical analysis, data analysis and Design of Experiments (DoE) for process optimisation using relevant software

• Hands on experience with Sartorius fermenters such as Biostat B – DCU and D- DCU would be desirable

• The ability to convey information clearly and effectively both in speaking and writing, to articulate goals and facilitate open discussions

• The ability to inspire, motivate and lead the team by example

• Foster a collaborative environment and encourage positive relationships

• The ability to adapt to new situations and being open to change and manage transitions smoothly

In order to commence working with us, the successful candidate will have the right to work in the UK.

What we offer

As a growing global life science company, stock listed on the German DAX and TecDAX, Sartorius offers a wide range of benefits:

• Personal and Professional Development: mentoring, leadership programs, LinkedIn Learning, internal seminar offerings

• Welcoming Culture: Mutual support, team-spirit and international collaboration; communities on numerous topics such as coaching, agile working and businesswomen network

• Health & Well-Being: Wide section of health and well-being support such as healthcare plans and health assessment services

• Intelligent working environment: Working in smart buildings with the latest technology and equipment (please check if applicable for position)

Albumedix

Benefits

Attractive Working Conditions:

• 35 hours working week

• 25 days annual leave, plus public holidays

• Free parking on site, easily accessible from the city centre and transport hubs

• Social Committee – With both free and subsidised social events

• Private Healthcare

• Pension Scheme

• Free onsite fitness classes

• Group Life Assurance

• Group Income Protection

• Free annual flu vaccinations

• Employee Assistance Programme for colleagues and their families

• One day per year given to be a ‘Helping Heart’ within your local community

About Sartorius

Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide.

We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment.

Join our global team and become part of the solution. We are looking forward to receiving your application. www.sartorius.com/careers

to our Candidate Portal and thank you for your interest in working and growing with us. We look forward to receiving your application. You can check the status anytime in this portal.

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Information on the application process can also be found in this video and under FAQ & Contact (https://www.sartorius.com/en/company/careers/faq) .

In this brochure (https://www.sartorius.com/resource/static/celum/202114/23_EN_Candidate_Booklet_Digital_web.pdf) you will learn more about us as an employer and your career with us. For further insights, please visit the Sartorius Blog (http://www.sartorius.com/en/company/newsroom/blog) and our career website (http://www.sartorius.com/en/company/careers) .

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